To be eligible for the MCA degree program at Royal School of Information & Management Sciences in Tirupati, candidates must have a bachelor's degree in any discipline from a recognized university with a minimum of 50% aggregate marks. Additionally, candidates must have studied Mathematics as a subject at the 10+2 level or during their graduation. They must also qualify in a national level entrance exam such as NIMCET or APICET. Relevant work experience in the field of computer applications may also be considered during the admission process.